Cell Culture Stainless Steel Bioreactors
The cell culture stainless steel bioreactors are designed for commercial application and industrial manufacturing with stronger performance.
Standard Stainless Steel Vessel
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Available from 10L to 300L (up 20tons), up to 70% working volume (larger volume available).
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Batch, fed-batch, continuously-batch, semi-continuous and high-density batch systems.
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Sterilization-In-Place (SIP), equipped with high temperature steam pipeline.
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Standard sensor ports for precise measurement and control of temperature, pH, DO, antifoam, feed, aeration and pressure.
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Optional Clear-In-Place (CIP), one port for cleaning device is provided at the top of the tank.
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Jacket vessel allows hot water and cooler to adjust the temperature.
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Standard with mechanical stirring, special stirring shaft material and precision processing. it has ideal dynamic balance performance with proper ratio of upper and lower shaft.
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Standard with flat or pitched-blade- impellers; other type impellers are available.
Features of Controlling Tower
Smart PID control
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Temperature, stirring speed, Ph, DO and other parameters in the tank can be controlled by subsection curve setting according to the process requirements.
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Temperature Control: Adopt PID automatic control mode; SS316L jacket base for electric heating and cold water for cooling.
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Dissolved oxygen control: equipped with DO electrode and shielded conductor, DO is associated with stirring motor speed, feeding, airflow, tank pressure and other parameters.
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PH value control: Intelligent PID system control built-in control peristaltic pumps for acid-alkali adjustment, with high control precision.
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Antifoam control: Foams are automatically detected and the peristaltic pump is controlled to add defoamer in proportion to time.
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Feeding control: Peristaltic pump switch control (manual, automatic, and off); accumulation volume control; coupled with other parameters (DO, pH, etc).
Multiple Control Function
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Associated control: temperature, stirring speed, pH, dissolved oxygen, defoaming, airflow, tank pressure, feed amount and other direct parameters.
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Remote monitoring: Suitable for smartphones, tablets, laptops and PC for instant remote monitoring.
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Step control: Users can switch directly between manual control and step control and set at least 10-step control program for temperature, agitation, PH, DO and feeding.
For Cell Culture
For Cell Culture
Clean In Place
Upgrading Option List
Standard Type Specifications
Model | BR500Pro-C1 | BR500Pro-C2 |
|---|---|---|
Controller | One console for one vessel | One console for two vessels |
Display / Operation | Touch panel 10" / Touch screen | Touch panel 10" / Touch screen |
Gas inlet | 1 overlay with 4 deep gas inlets | 1 overlay with 4 deep gas inlets for each vessel |
USB | 1 x RS485 | 2 x RS485 |
Vessel | 10L - 300L, max. 20tons | 2 * (10L - 300L, max. 20tons) |
Working volume | 9.8L / 13.5L / 20.3L / 25.5L ... | 2 x 9.8L / 13.5L / 20.3L / 25.5L ... |
Stirring speed | 5 - 1000 rpm | 5 - 1000 rpm |
Motor power (Kw) | 0.75/1/1/1/0.75/1.5 | 0.75/1/1/1/0.75/1.5 |
Pressure | 0.30Mpa | 0.30Mpa |
Material | SS304 & SS316L stainless steel | SS304 & SS316L stainless steel |
Serilization | Sterilization in place | Sterilization in place |
Feeding pumps | 4 peristaltic pumps | 8 peristaltic pumps |
Peristic pump tube ID | 0.5 mm | 0.8 mm |
Peristic pump flow rare | 0.06/revolution | 0.15/revolution |
Sensors | PT100, DO, foam, pH | PT100, DO, foam, pH |
Temperature | Eletrical heating sleeve with bottom water to control heating / cooling | Eletrical heating sleeve with bottom water to control heating / cooling |
pH control | Range: 2 - 12（±0.01)，display: 0 - 14（±0.01) | Range: 2 - 12（±0.01)，display: 0 - 14（±0.01) |
DO control | Range: 0 - 150% (±3%), international eletrode and shielded wire detection | Range: 0 - 150% (±3%), international eletrode and shielded wire detection |
Defoam control | Automatic foam detection, automatically add defoamer in proportion to time | Automatic foam detection, automatically add defoamer in proportion to time |
Agitation control | Servo motor, PID control, stepless speed regulation | Servo motor, PID control, stepless speed regulation |
Areation airflow | 2VVM | 2VVM |
Areation filter | 0.2μm | 0.2μm |
Areation | 0.5SLPM, 1.0SLPM, 2.5SLPM, 5.0SLPM, 10SLPM, 25SLPM (customizable) | 0.5SLPM, 1.0SLPM, 2.5SLPM, 5.0SLPM, 10SLPM, 25SLPM (customizable) |
Areation flowmeter | Air calibrated, 1.2bar 20℃ | Air calibrated, 1.2bar 20℃ |