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Airlift Fermenter 
& Bioreactor

BR500ALB Series Airlift Fermenter & Bioreactor

BR500ALB series airlift fermenter & bioreactor is a gas-liquid bioreactor based on the principle of ventilation pipes, without any mechanical stirring. Compressed air is used for aeration and agitation. The turbulence caused by the gas/fluid flow ensures adequate mixing of the liquid.  The gas used for agitation can act to either, introduce new molecules to the mixture inside of the bioreactor, or remove specific metabolic molecules produced by microorganisms.

Key Facts 

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  • Efficient gas-liquid dispersion with low power consumption

  • Low shear rate (have homogeneous shear and stress forces throughout the entire bioreactor.)

  • Improved fluidization characteristics

  • Excellent liquid-solid and gas-liquid mass transfer

Features

15-Inch Touch Screen

Provides a user-friendly interface for simplified control and real-time monitoring of the bioreaction process.

Special Stirring System

Utilizes an airlift principle for stirring, reducing energy consumption and contamination risk while achieving high mass transfer efficiency with minimal shear force.

Efficient Air Sterile Regulation

An external air compressor and sterilization system ensure sterile conditions for optimal microbial or cell growth.

Fully Automatic Sterilization in Place

Uses external steam for sterilization in place, reducing manual operations and contamination risks.

Stable and Reliable Hardware

Features high-quality components like Siemens PLC controllers and Swiss Hamilton electrodes for precision and durability.

Intelligent PID Control

Manages heating, cooling, pH, dissolved oxygen (DO), foam, and tank pressure to maintain optimal process conditions.

Structure 

Airlift Bioreactor Diagram

An airlift bioreactor works by stirring cultured substance using gas. Air/Gas is fed through a sparger ring into the bottom of a concentric tube, which directs the circulation of both air bubbles and liquid. At the top of the bioreactor, there is a gas separator to remove gaseous substances.

 

Air bubbles flow upwards within the central draft tube; some of these bubbles coalesce at the top of the column and exit, while others follow the degassed liquid and circulate downward from the area outside the draft tube.

Classification

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Single stage type

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Multiple stage type

Model
BR500ALB-3L / 7L / 10L / 20L / 30L / 50L / 100L / 200L / 300L / 500L
Tank body configuration
1x pH electrode port; 1x DO electrode port; 1x temperature electrode port; 1x air inlet; 1x water inlet; 1x water outlet; 1x sampling valve port; 1x discharge valve port; 1x Sight glass;
Working volume
75-90%
Tank
Internal (recommended) or external circulation
Diameter-to-height ratio
1:3 to 1:5
Design pressure
Inner cylinder 0.3 MPa, jacket 0.4 MPa
Working pressure
Inner cylinder 0.25 MPa, jacket 0.3 MPa
Material
Inner cylinder SUS316L, jacket SUS304, fine polishing inside and outside
Cover configuration
1x inoculation por; 1x foam electrode port; 1x exhaust port, including exhaust condenser; 2x CIP spray port; 1x lamp port; 4x feed port;
Volume
3L, 5L, 7L, 10L, 15L, 20L, 30L, 50L, 100L, 200L, 300L, 500L or larger

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Service

Onsite Installation and Trainig

Complete Production and Inspection Process

30+ Years Experience; Experienced Engineers

Customization Capability

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