Airlift Fermenter
& Bioreactor

BR500ALB Series Airlift Fermenter & Bioreactor

BR500ALB series airlift fermenter & bioreactor is a gas-liquid bioreactor based on the principle of ventilation pipes, without any mechanical stirring. Compressed air is used for aeration and agitation. The turbulence caused by the gas/fluid flow ensures adequate mixing of the liquid. The gas used for agitation can act to either, introduce new molecules to the mixture inside of the bioreactor, or remove specific metabolic molecules produced by microorganisms.

Key Facts

Efficient gas-liquid dispersion with low power consumption
Low shear rate (have homogeneous shear and stress forces throughout the entire bioreactor.)
Improved fluidization characteristics
Excellent liquid-solid and gas-liquid mass transfer

Get A Quote

Features

15-Inch Touch Screen

Provides a user-friendly interface for simplified control and real-time monitoring of the bioreaction process.

Special Stirring System

Utilizes an airlift principle for stirring, reducing energy consumption and contamination risk while achieving high mass transfer efficiency with minimal shear force.

Efficient Air Sterile Regulation

An external air compressor and sterilization system ensure sterile conditions for optimal microbial or cell growth.

Fully Automatic Sterilization in Place

Uses external steam for sterilization in place, reducing manual operations and contamination risks.

Stable and Reliable Hardware

Features high-quality components like Siemens PLC controllers and Swiss Hamilton electrodes for precision and durability.

Intelligent PID Control

Manages heating, cooling, pH, dissolved oxygen (DO), foam, and tank pressure to maintain optimal process conditions.

Structure

Airlift Bioreactor Diagram

An airlift bioreactor works by stirring cultured substance using gas. Air/Gas is fed through a sparger ring into the bottom of a concentric tube, which directs the circulation of both air bubbles and liquid. At the top of the bioreactor, there is a gas separator to remove gaseous substances.

Air bubbles flow upwards within the central draft tube; some of these bubbles coalesce at the top of the column and exit, while others follow the degassed liquid and circulate downward from the area outside the draft tube.

Classification

Single stage type

Multiple stage type

Model	BR500ALB-3L / 7L / 10L / 20L / 30L / 50L / 100L / 200L / 300L / 500L
Tank body configuration	1x pH electrode port; 1x DO electrode port; 1x temperature electrode port; 1x air inlet; 1x water inlet; 1x water outlet; 1x sampling valve port; 1x discharge valve port; 1x Sight glass;
Working volume	75-90%
Tank	Internal (recommended) or external circulation
Diameter-to-height ratio	1:3 to 1:5
Design pressure	Inner cylinder 0.3 MPa, jacket 0.4 MPa
Working pressure	Inner cylinder 0.25 MPa, jacket 0.3 MPa
Material	Inner cylinder SUS316L, jacket SUS304, fine polishing inside and outside
Cover configuration	1x inoculation por; 1x foam electrode port; 1x exhaust port, including exhaust condenser; 2x CIP spray port; 1x lamp port; 4x feed port;
Volume	3L, 5L, 7L, 10L, 15L, 20L, 30L, 50L, 100L, 200L, 300L, 500L or larger

Aerobic Fermentation

Highly Oxygen-Dependent Processes: Airlift bioreactors are particularly suitable for aerobic fermentation processes where oxygen transfer is a critical factor. Their design allows for efficient oxygen distribution throughout the medium.
Shear-Sensitive Cultures: Ideal for processes involving shear-sensitive microorganisms like filamentous fungi and certain bacteria, as the gentle circulation minimizes cell damage.

Continuous Fermentation

Airlift bioreactors are well-suited for continuous fermentation processes due to their efficient mixing and ability to maintain a stable environment for prolonged periods

Aerobic Fermentation

Airlift bioreactors are effective for cultivating microalgae for the production of biofuels, food supplements, and pigments. The design ensures adequate light penetration and gas exchange, which are crucial for algal growth.

Title	Text
Stirring control	Control mode: built-in guide barrel, gas is introduced from the bottom
pH control	Control mode: PID control, associated with acid and alkali pump, supports feed association
	Display range: 0.00-14.00, ±0.01
	Control range: 2.00-12.00, ±0.01
DO control	Control mode: PID control, associated with speed, Air, O2, supports feed association
	Display range: 0-150%, ±0.1%
	Control range: 0-150%, ±3%
Temperature control	Control mode: PID control, heater and circulation pump realize jacket water circulation
	Display range: 0-150℃, ±0.1℃
	Control range: (cooling water + 5℃) -65.0℃±0.2℃
Foam control	Control mode: mechanical defoaming paddle; PID control, peristaltic pump automatically adds defoaming agent
Intake control	Gas type: air
	Control mode: rotor flowmeter display, manual control
	Inlet method: from bottom
	Filter: shell 316L, filter cartridge 0.2 μm, PTFE
Exhaust control	Control mode: automatic pressure control and manual control bypass, including exhaust gas condenser
	Detection method: pressure sensor and mechanical pressure gauge
	Display range: 0-0.4 MPa, ±0.01bar
	Control range: 0-0.25 MPa, ±0.05bar
	Filter: housing 316L, filter element 0.2 μm, PTFE
Disinfection method	External steam, automatic SIP
Controller	Using Siemens PLCs (Programmable Logic Controllers) for controlling, enhancing automation, efficiency, and precision in the fermentation process.